<\/p>
\u534e\u76db\u987f—\u5c71\u4e1c“\u95ee\u9898\u75ab\u82d7”\u4e8b\u4ef6\u7684\u55a7\u56a3\u8fd8\u672a\u5e73\u606f\uff0c\u5c31\u6709\u5a92\u4f53\u66dd\u51fa\u4e2d\u56fd\u8fdb\u53e3\u836f\u7269\u5ba1\u6279\u73af\u8282\u7684\u6f0f\u6d1e\uff0c\u79f0\u4e0d\u5c11\u5728\u6d77\u5916\u672a\u83b7\u6279\u7684\u836f\u7269\u5728\u4e2d\u56fd\u83b7\u5f97\u65b0\u751f\u3002\u8fd9\u4e00\u6d88\u606f\u7ed9\u5df2\u9677\u5165“\u4fe1\u4efb\u5371\u673a”\u7684\u4e2d\u56fd\u533b\u7597\u7cfb\u7edf\u53c8\u4e00\u91cd\u51fb\u3002\u6c11\u4f17\u4e5f\u8868\u793a\u4e0d\u6ee1\uff0c\u6307\u8d23\u836f\u76d1\u5c40\u4e3a\u5229\u76ca\u4e0d\u987e\u5b89\u5168\uff0c\u5c06\u56fd\u4eba\u5f53\u4f5c“\u5b9e\u9a8c\u5c0f\u767d\u9f20”\u3002<\/span><\/p> <\/p> \u7f8e\u56fd\u300a\u534e\u5c14\u8857\u65e5\u62a5\u300b\u65e5\u524d\u62a5\u9053\uff0c\u7f8e\u56fd\u533b\u836f\u4f01\u4e1a\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d\uff08<\/span>Bristol-Myers Squibb<\/span>\uff09\u5c06\u4e09\u5e74\u524d\u5c31\u5df2\u505c\u6b62\u5168\u7403\u8bd5\u9a8c\u7684\u6297\u809d\u764c\u836f\u7269“\u5e03\u7acb\u5c3c\u5e03”\uff08<\/span>Brivanib<\/span>\uff09\u8bb8\u53ef\u6743\u6388\u4e88\u4e2d\u56fd\u516c\u53f8\u518d\u9f0e\u533b\u836f\u3002\u8be5\u836f\u88ab\u53eb\u505c\u5168\u7403\u8bd5\u9a8c\u7684\u539f\u56e0\u662f\u836f\u6548\u4e0d\u53ca\u5bf9\u624b\u62dc\u8033\u96c6\u56e2\u548c<\/span>Onyx<\/span>\u5236\u836f\u516c\u53f8\u7814\u53d1\u7684“\u857e\u838e\u74e6”\uff08<\/span>Sorafenib<\/span>\uff09\u3002\u540c\u6837\uff0c\u56e0\u4f1a\u5f15\u8d77\u8840\u6db2\u75be\u75c5\u800c\u5728\u4e0a\u4e16\u7eaa<\/span>90<\/span>\u5e74\u4ee3\u5c31\u5df2\u9000\u51fa\u6b27\u6d32\u5e02\u573a\u7684\u4e2d\u98ce\u6cbb\u7597\u836f\u7269“\u6842\u54cc\u9f50\u7279”\uff08<\/span>Cinepazide<\/span>\uff09\uff0c<\/span>2010<\/span>\u5e74\u88ab\u5f15\u8fdb\u4e2d\u56fd\u540e\u4e5f\u6210\u4e3a\u7545\u9500\u836f\u3002<\/span><\/p> <\/p> \u518d\u9f0e\u516c\u53f8\u521b\u59cb\u4eba\u675c\u83b9\u5bf9\u300a\u534e\u5c14\u8857\u65e5\u62a5\u300b\u8868\u793a\uff0c\u4ed6\u4eec\u5f15\u8fdb\u8be5\u836f\u662f\u770b\u4e2d\u5b83\u7684\u4ef7\u683c\u76f8\u5bf9\u5408\u7406\u3002\u800c\u8425\u9500\u4e2d\u98ce\u6cbb\u7597\u836f\u7269“\u6842\u54cc\u9f50\u7279”\u7684\u4e2d\u56fd\u516c\u53f8\u56db\u73af\u533b\u836f\u4e5f\u8868\u793a\uff0c\u4e2d\u56fd\u751f\u4ea7\u7684“\u6842\u54cc\u9f50\u7279”\u7eaf\u5ea6\u66f4\u9ad8\uff0c\u4e5f\u5f97\u5230\u4e86\u4e2d\u56fd\u76f8\u5173\u90e8\u95e8\u548c\u60a3\u8005\u7684\u8ba4\u53ef\u3002<\/span><\/p> <\/p> \u4e2d\u56fd\u836f\u7269\u5ba1\u6279\u95e8\u69db\u4f4e<\/span> \u8150\u8d25\u662f\u6839\u6e90<\/span><\/p> <\/p> \u4e0e\u6b27\u7f8e\u4e00\u4e9b\u56fd\u5bb6\u76f8\u6bd4\uff0c\u533b\u836f\u4f01\u4e1a\u8981\u60f3\u5728\u4e2d\u56fd\u83b7\u5f97\u51c6\u5165\u5e76\u975e\u96be\u4e8b\u3002\u300a\u7b2c\u4e00\u8d22\u7ecf\u65e5\u62a5\u300b\u53bb\u5e74<\/span>7<\/span>\u6708\u66fe\u63ed\u9732\u4e2d\u56fd\u836f\u7269\u8bd5\u9a8c\u6570\u636e\u9020\u5047\uff0c\u79f0“<\/span>5000<\/span>\u5143\u5c31\u53ef\u4ee5\u4e70\u5230\u4e00\u4efd\u7533\u62a5\u8d44\u6599”\uff0c\u5df2\u7ecf\u662f\u4e1a\u5185\u516c\u5f00\u7684\u79d8\u5bc6\u3002\u62a5\u9053\u63f4\u5f15\u4e00\u4f4d\u957f\u671f\u4ece\u4e8b\u836f\u54c1\u7814\u53d1\u4eba\u5458\u7684\u8bdd\u8bf4\uff1a“\u4e34\u5e8a\u6570\u636e\u592a\u4e71\u4e86\uff0c\u6211\u4f30\u8ba1<\/span>50%<\/span>\u4ee5\u4e0a\u90fd\u9020\u5047\u3002”<\/span><\/p> <\/p> \u8fd9\u4f4d\u7814\u53d1\u4eba\u5458\u8fd8\u8868\u793a\uff0c\u8150\u8d25\u662f\u9020\u5047\u7684\u6839\u6e90\u3002\u836f\u7269\u5ba1\u6279\u90e8\u95e8\u9996\u8981\u5173\u5fc3\u7684\u5e76\u975e\u836f\u7269\u5b89\u5168\u6027\uff0c\u800c\u662f\u5229\u76ca\u662f\u5426\u8db3\u591f\u5927\u3002“\u5927\u5bb6\u90fd\u89c9\u5f97\uff0c\u4e0d\u662f\u5728\u5ba1\u67e5\u6280\u672f\u8d44\u6599\uff0c\u800c\u662f\u5728\u6bd4\u62fc\u8c01\u80fd\u591f\u8fdb\u5165\u8fd9\u4e2a\u8150\u8d25\u5708\u5b50\u8fdb\u884c\u8150\u8d25\uff0c\u8bd5\u9a8c\u6570\u636e\u5c31\u6ca1\u90a3\u4e48\u91cd\u8981\u4e86\uff0c”\u4ed6\u8bf4\u3002<\/span><\/p> <\/p> 2007<\/span>\u5e74\uff0c\u524d\u56fd\u5bb6\u836f\u76d1\u5c40\u5c40\u957f\u90d1\u7b71\u8438\u88ab\u5224\u5904\u6b7b\u5211\uff0c\u56e0\u5176\u6d89\u5acc\u5728\u836f\u54c1\u3001\u533b\u7597\u5668\u68b0\u5ba1\u6279\u7b49\u65b9\u9762\u8c0b\u53d6\u5229\u76ca\u3002\u4eba\u6c11\u7f51\u968f\u540e\u520a\u767b\u4e86\u90d1\u7b71\u8438\u9057\u4e66\uff0c\u4ed6\u5199\u9053\uff1a“\u7531\u4e8e\u6211\u7684\u73a9\u5ffd\u804c\u5b88\uff0c\u7531\u4e8e\u6211\u7684\u884c\u653f\u4e0d\u4f5c\u4e3a\uff0c\u4f7f\u5047\u836f\u76db\u884c\uff0c\u917f\u6210\u4e86\u4e00\u8d77\u53c8\u4e00\u8d77\u60e8\u6848……\u6211\u73b0\u5728\u6700\u5bb3\u6015\u7684\u662f\uff0c\u6211\u5c06\u5982\u4f55\u9762\u5bf9\u90a3\u4e9b\u88ab\u6211\u5bb3\u6b7b\u7684\u51a4\u9b42\u3002”<\/span><\/p> <\/p> \u90d1\u7b71\u8438\u5728\u4efb\u671f\u95f4\uff0c\u903e<\/span>15<\/span>\u4e07\u79cd\u836f\u7269\u83b7\u5f97\u6279\u51c6\u3002\u7ecf\u5176\u6279\u51c6\u7684\u9f50\u9f50\u54c8\u5c14\u7b2c\u4e8c\u5236\u836f\u6709\u9650\u516c\u53f8\u4eae\u83cc\u7532\u7d20\u6ce8\u5c04\u6db2\u4e8b\u4ef6\uff0c\u548c\u5b89\u5fbd\u534e\u6e90\u751f\u7269\u836f\u4e1a\u6709\u9650\u516c\u53f8“\u6b23\u5f17”\u6ce8\u5c04\u6db2\u4e8b\u4ef6\u5bfc\u81f4<\/span>10<\/span>\u4eba\u6b7b\u4ea1\uff0c\u591a\u4eba\u51fa\u73b0\u80be\u529f\u80fd\u8870\u7aed\u3002<\/span><\/p> <\/p> \u4eca\u5e74\u6e05\u660e\u8282\u524d\u5915\uff0c\u6842\u6797\u836f\u76d1\u5c40\u5c40\u957f\u5510\u5929\u751f\u5760\u697c\u6b7b\u4ea1\uff0c\u6b7b\u4ea1\u539f\u56e0\u6b63\u5728\u8c03\u67e5\u4e2d\u3002\u5510\u5929\u751f<\/span>2013<\/span>\u5e74\u4efb\u5e7f\u897f\u9f99\u80dc\u5404\u65cf\u81ea\u6cbb\u53bf\u53bf\u59d4\u4e66\u8bb0\u65f6\uff0c\u56e0\u516c\u6b3e\u5403\u559d\u8fdd\u89c4\u88ab\u514d\u804c\uff0c\u540e\u6539\u4efb\u6842\u6797\u836f\u76d1\u5c40\u5c40\u957f\u3002<\/span><\/p> <\/p> \u8fd1\u51e0\u5e74\uff0c\u836f\u76d1\u5c40\u6210\u4e3a\u4e86\u8150\u8d25\u7684\u91cd\u707e\u533a\u3002<\/span>2002<\/span>\u5e74<\/span>8<\/span>\u6708\uff0c\u539f\u6d59\u6c5f\u7701\u836f\u76d1\u5c40\u5c40\u957f\u56e0\u5de8\u989d\u53d7\u8d3f\u88ab\u5224\u6b7b\u7f13\uff1b<\/span>2006<\/span>\u5e74<\/span>6<\/span>\u6708\uff0c\u539f\u5409\u6797\u7701\u836f\u76d1\u5c40\u526f\u5c40\u957f\u4e8e\u5e86\u9999\u56e0\u53d7\u8d3f\u7f6a\u548c\u5de8\u989d\u8d22\u4ea7\u6765\u6e90\u4e0d\u660e\u7f6a\u83b7\u5211\u6709\u671f\u5f92\u5211<\/span>15<\/span>\u5e74\uff1b<\/span>2006<\/span>\u5e74<\/span>7<\/span>\u6708\uff0c\u539f\u9655\u897f\u7701\u836f\u76d1\u5c40\u6ce8\u518c\u5904\u5904\u957f\u7c73\u517b\u7d20\u56e0\u53d7\u8d3f\u7f6a\u88ab\u5224\u5904\u6709\u671f\u5f92\u5211<\/span>10<\/span>\u5e74\uff1b<\/span>2006<\/span>\u5e74<\/span>12<\/span>\u6708\uff0c\u539f\u56fd\u5bb6\u836f\u76d1\u5c40\u533b\u7597\u5668\u68b0\u53f8\u53f8\u957f\u90dd\u548c\u5e73\u56e0\u53d7\u8d3f\u7f6a\u548c\u975e\u6cd5\u79c1\u85cf\u67aa\u652f\u7f6a\u88ab\u5224\u5904\u6709\u671f\u5f92\u5211<\/span>15<\/span>\u5e74\uff1b<\/span>2007<\/span>\u5e74<\/span>7<\/span>\u6708\uff0c\u539f\u56fd\u5bb6\u836f\u76d1\u5c40\u836f\u54c1\u6ce8\u518c\u53f8\u53f8\u957f\u66f9\u6587\u5e84\u56e0\u53d7\u8d3f\u7f6a\u548c\u73a9\u5ffd\u804c\u5b88\u7f6a\u88ab\u5224\u5904\u6b7b\u7f13\u3002<\/span><\/p> <\/p> \u539f\u536b\u751f\u90e8\u90e8\u957f\u5468\u5f3a\u66fe\u516c\u5f00“\u5410\u69fd”\u4e2d\u56fd\u836f\u7269\u5ba1\u6279\u8150\u8d25\uff0c\u8bf4“\u5168\u56fd\u76ee\u524d\u4e03\u516b\u5343\u79cd\u836f\uff0c\u4f46\u5374\u6279\u51fa\u6765\u5341\u516b\u4e5d\u4e07\u4e2a\u836f\u53f7\u3002\u4e00\u79cd\u836f\u6709\u51e0\u5341\u4e2a\u53f7\uff0c\u540c\u6837\u7684\u836f\u54c1\u836f\u4ef7\u76f8\u5dee\u5341\u51e0\u500d\u3002”\u9ad8\u5f3a\u76f4\u8a00\uff0c“\u51e0\u4e2a\u4eba\u5173\u7740\u95e8\u6279\u836f\uff0c\u80fd\u4e0d\u8150\u8d25\uff1f”<\/span><\/p> <\/p> \u56fd\u5bb6\u836f\u76d1\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\u7f51\u7ad9\u663e\u793a\uff0c\u76ee\u524d\u5728\u5ba1\u54c1\u79cd<\/span>15946<\/span>\u4e2a\uff0c\u5176\u4e2d\u8fdb\u53e3\u54c1\u79cd<\/span>1592<\/span>\u6761\u3002\u300a\u7b2c\u4e00\u8d22\u7ecf\u65e5\u62a5\u300b\u5728\u62a5\u9053\u4e2d\u8bf4\uff0c\u56fd\u5bb6\u836f\u76d1\u5c40\u8d1f\u8d23\u836f\u54c1\u5ba1\u8bc4\u7684\u4eba\u5458\u53ea\u6709<\/span>120<\/span>\u4eba\u3002\u5982\u6b64\u60ac\u6b8a\u7684\u5de5\u4f5c\u91cf\uff0c\u300a\u7b2c\u4e00\u8d22\u7ecf\u65e5\u62a5\u300b\u63f4\u5f15\u4e00\u4f4d\u63a5\u8fd1\u836f\u76d1\u5c40\u7684\u4eba\u58eb\u7684\u8bdd\u8bf4\uff1a“\u73b0\u5728\u5ba1\u6279\u73af\u8282\u4eba\u624b\u4e0d\u591f\uff0c\u4e0d\u53ef\u80fd\u4e00\u4e2a\u4e2a\u8fdb\u884c\u6838\u67e5\u3002”<\/span><\/p> <\/p> \u53bb\u5e74\u836f\u76d1\u5c40\u53d1\u5e03\u4e86\u300a\u5173\u4e8e\u5f00\u5c55\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\u81ea\u67e5\u6838\u67e5\u5de5\u4f5c\u7684\u516c\u544a\u300b\uff0c\u79f0\u5c06\u4e25\u60e9\u63d0\u4ea4\u865a\u5047\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\u7684\u516c\u53f8\u3002\u836f\u76d1\u5c40\u79f0\uff0c\u300a\u516c\u544a\u300b\u53d1\u5e03\u540e\uff0c\u5236\u836f\u516c\u53f8\u64a4\u56de\u4e86\u8fd1\u4e94\u5206\u4e4b\u56db\u7684\u836f\u54c1\u62a5\u6279\u7533\u8bf7\u3002<\/span><\/p> <\/p> \u53e6\u4e00\u79cd\u58f0\u97f3\uff1a\u4e0d\u80fd\u8fde\u8ba9\u56fd\u6c11\u505a“\u5c0f\u767d\u9f20”\u7684\u8d44\u683c\u4e5f\u5265\u593a<\/span><\/p> <\/p> “\u56fd\u5916\u672a\u83b7\u6279\u836f\u7269\u6d41\u5165\u4e2d\u56fd”\u7684\u62a5\u9053\u520a\u53d1\u540e\uff0c\u5927\u591a\u6570\u7f51\u53cb\u7eb7\u7eb7\u6307\u8d23\u836f\u76d1\u5c40\u5ba1\u6279\u4e0d\u529b\uff0c\u7f6e\u60a3\u8005\u751f\u547d\u5b89\u5168\u4e8e\u4e0d\u987e\u3002\u4f46\u540c\u65f6\uff0c\u6c11\u95f4\u4e5f\u6709\u53e6\u4e00\u79cd\u89c2\u70b9\uff0c\u8ba4\u4e3a\u5728\u56fd\u5916\u672a\u83b7\u6279\u7684\u836f\u7269\u5927\u591a\u662f\u7531\u4e8e\u7597\u6548\u5dee\uff0c\u800c\u975e\u5f7b\u5e95\u65e0\u6548\u3002\u4e2d\u56fd\u5e02\u573a\u5bf9\u836f\u7269\u9700\u6c42\u6781\u9ad8\uff0c\u540c\u65f6\u4f4e\u6536\u5165\u60a3\u8005\u7fa4\u4f53\u5e9e\u5927\uff0c\u56e0\u6b64“\u79bb\u5f00\u836f\u54c1\u4ef7\u683c\u8c08\u6548\u679c\u5e76\u4e0d\u5ba2\u89c2”\u3002<\/span><\/p> <\/p> \u7f8a\u57ce\u665a\u62a5\u9996\u5e2d\u8bc4\u8bba\u5458“\u5251\u5ba2”\u5199\u6587\u7ae0\u8bf4\uff0c\u56e0\u67d0\u4e9b\u526f\u4f5c\u7528\u5728\u56fd\u5916\u9000\u51fa\u5e02\u573a\u7684\u836f\u54c1\u4e0d\u7b49\u4e8e\u52a3\u8d28\u836f\u3002“\u5251\u5ba2”\u8ba4\u4e3a\uff0c\u8bc4\u4ef7\u836f\u7269\u597d\u574f\u5e94\u770b\u4e09\u70b9\uff1a\u6548\u679c\u3001\u526f\u4f5c\u7528\u548c\u4ef7\u683c\u3002“\u662f\u836f\u4e09\u5206\u6bd2”\uff0c\u800c\u4ef7\u683c\u5728\u5f88\u591a\u65f6\u5019\u4f1a\u6210\u4e3a\u836f\u54c1\u597d\u574f\u7684\u51b3\u5b9a\u56e0\u7d20\uff1a“\u518d\u597d\u7684\u836f\uff0c\u5982\u679c\u60a3\u8005\u7528\u4e0d\u8d77\uff0c\u90a3\u4e5f\u662f\u626f\u6de1”\u3002<\/span><\/p> <\/p> \u5728\u793e\u4ea4\u5a92\u4f53\u4e0a\uff0c\u4e5f\u6709\u4e00\u4e9b\u8ba4\u4e3a\u836f\u7269\u5ba1\u6279\u95e8\u69db\u4f4e\u5e76\u975e“\u5927\u4e8b”\u7684\u89c2\u70b9\u3002<\/span><\/p> <\/p> \u7f51\u53cb<\/span>@<\/span>\u7af9\u6728\u77f3\u5934\u8bf4\uff1a“\u8fd9\u4e0d\u662f\u5565\u4e8b\u5427\uff0c\u4f60\u770b\u90a3\u4e9b\u4e2d\u836f\uff0c\u6709\u54ea\u4e2a\u662f\u7ecf\u8fc7\u4e86\u836f\u6548\u68c0\u6d4b\u6216\u8005\u6bd2\u6027\u68c0\u6d4b\u7684\uff1f\u4e0d\u4e5f\u76f4\u63a5\u8fdb\u5165\u5e02\u573a\u4e86\u5417\uff1f”<\/span><\/p> <\/p> \u7f51\u53cb<\/span>@<\/span>\u7231\u751f\u6d3b\u7231\u5496\u5561<\/span>2015 <\/span>\u8bf4\uff1a“\u4e70\u5f97\u8d77\u7684\u836f\u7269\u4f1a\u6bd4\u8fc7\u4e8e\u6602\u8d35\u7684\u7279\u6548\u836f\u66f4\u53d7\u4eba\u6b22\u8fce\u3002”<\/span><\/p> <\/p> \u7f51\u53cb<\/span>@lygby0001 <\/span>\u8bf4\uff1a“\u56fd\u5bb6\u6279\u51c6\u7597\u6548\u7a0d\u5dee\u4f46\u4ef7\u683c\u4f4e\u7684\u8fdb\u53e3\uff0c\u6211\u8ba4\u4e3a\u8fd9\u79cd\u505a\u6cd5\u662f\u5bf9\u7684\u3002”<\/span><\/p>","protected":false},"excerpt":{"rendered":" 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